Activator of G-protein signaling 8 is involved in VEGF-mediated signal processing during angiogenesis.

@article{Hayashi2016ActivatorOG,
  title={Activator of G-protein signaling 8 is involved in VEGF-mediated signal processing during angiogenesis.},
  author={Hisaki Hayashi and Abdullah Al Mamun and Miho Sakima and Motohiko Sato},
  journal={Journal of cell science},
  year={2016},
  volume={129 6},
  pages={1210-22}
}
Activator of G-protein signaling 8 (AGS8, also known as FNDC1) is a receptor-independent accessory protein for the Gβγ subunit, which was isolated from rat heart subjected to repetitive transient ischemia with the substantial development of collaterals. Here, we report the role of AGS8 in vessel formation by endothelial cells. Knockdown of AGS8 by small… CONTINUE READING