Activation thresholds of K(V), BK andCl(Ca) channels in smooth muscle cells in pial precapillary arterioles.

@article{Cheong2002ActivationTO,
  title={Activation thresholds of K(V), BK andCl(Ca) channels in smooth muscle cells in pial precapillary arterioles.},
  author={Alex Cheong and Kirsty Quinn and Alexandra M. Dedman and David J Beech},
  journal={Journal of vascular research},
  year={2002},
  volume={39 2},
  pages={122-30}
}
We have previously shown expression of voltage-gated K+ channels (K(V)) in smooth muscle of cerebral arterioles and suggested the channels function to oppose voltage-dependent Ca2+ entry. However, other studies indicate that large conductance Ca2+-activated K+ (BK) channels serve this function and chloride (Cl-) channels may have the opposite effect. In this study we compared the activation thresholds and absolute current amplitudes for K(V) channels, BK channels and Cl- channels at… CONTINUE READING