Activation state alters the effect of dietary fatty acids on pro-inflammatory mediator production by murine macrophages.
@article{Wallace2000ActivationSA, title={Activation state alters the effect of dietary fatty acids on pro-inflammatory mediator production by murine macrophages.}, author={F. Wallace and E. Miles and P. Calder}, journal={Cytokine}, year={2000}, volume={12 9}, pages={ 1374-9 } }
Studies investigating the effect of dietary fats on pro-inflammatory cytokine production by macrophages (M phis) have yielded conflicting results. We hypothesised that this may be due to the different capacities of the M phis studied commonly (resident, thioglycollate-elicited) to produce prostaglandin E(2)(PGE(2)) and leukotriene B(4)(LTB(4)) which inhibit and stimulate, respectively, tumour necrosis factor-alpha (TNF-alpha) and interleukin-1 beta (IL-1 beta) production. To investigate this… CONTINUE READING
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References
SHOWING 1-10 OF 30 REFERENCES
Effects of dietary lipid manipulation upon inflammatory mediator production by murine macrophages.
- Biology, Medicine
- Cellular immunology
- 1995
- 230
Dietary n-3 polyunsaturated fatty acids prevent the development of atherosclerotic lesions in mice. Modulation of macrophage secretory activities.
- Biology, Medicine
- Arteriosclerosis and thrombosis : a journal of vascular biology
- 1993
- 189
- PDF
Dietary fish oil enhances macrophage production of nitric oxide.
- Biology, Medicine
- The Journal of surgical research
- 1994
- 38
Alteration of tumor necrosis factor-alpha production by macrophages from mice fed diets high in eicosapentaenoic and docosahexaenoic fatty acids.
- Biology, Medicine
- Cellular immunology
- 1994
- 41
Modulation of inflammation and cytokine production by dietary (n-3) fatty acids.
- Medicine
- The Journal of nutrition
- 1996
- 209
- PDF
Fatty acid intake and Kupffer cell function: fish oil alters eicosanoid and monokine production to endotoxin stimulation.
- Biology, Medicine
- Surgery
- 1988
- 251
Interleukin-1 and tumor necrosis factor synthesis by mouse peritoneal macrophages is enhanced by dietary n-3 polyunsaturated fatty acids.
- Biology, Medicine
- Immunology letters
- 1990
- 103
Fish oil supplementation and essential fatty acid deficiency reduce nitric oxide synthesis by rat macrophages.
- Biology, Medicine
- Kidney international
- 1994
- 50
Increasing the dietary (n-3) to (n-6) polyunsaturated fatty acid ratio increases tumor necrosis factor production by murine resident peritoneal macrophages without an effect on elicited peritoneal macrophages.
- Biology, Medicine
- The Journal of nutrition
- 1992
- 70
Dietary supplementation with fish oil enhances in vivo synthesis of tumor necrosis factor.
- Biology, Medicine
- Immunology letters
- 1992
- 57