Activation pattern of caspases in human spermatozoa.

@article{Paasch2004ActivationPO,
  title={Activation pattern of caspases in human spermatozoa.},
  author={Uwe Paasch and Sonja Grunewald and Ashok Agarwal and Hans-J{\"u}rgen Glandera},
  journal={Fertility and sterility},
  year={2004},
  volume={81 Suppl 1},
  pages={
          802-9
        }
}
OBJECTIVE We investigated the activation of caspases 8, 9, 1, and 3 in human ejaculated spermatozoa to study main pathways of apoptosis. Potential functional impact of this phenomenon and possible activation mechanisms were examined by [1] subjecting cells to freezing and thawing, and [2] testing the dependence of caspase activity on membrane integrity. DESIGN Experimental study. SETTING Andrology Center Leipzig (European Academy of Andrology). PATIENT(S) Ten healthy volunteers, 40 semen… CONTINUE READING
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