Activation of yeast plasma membrane ATPase by acid pH during growth.

@article{Eraso1987ActivationOY,
  title={Activation of yeast plasma membrane ATPase by acid pH during growth.},
  author={Pilar Eraso and Carlos Gancedo},
  journal={FEBS letters},
  year={1987},
  volume={224 1},
  pages={187-92}
}
When yeast grows on media in which a final external pH lower than 4 is attained there is a 2-3-fold increase in plasma membrane ATPase activity. This acid-mediated activation produces a 2-fold increase in the ATPase affinity for ATP but does not modify its optimum pH. The acid-mediated activation is dependent on the stage of growth, only late logarithmic or stationary cells being capable of being activated by incubation in an acidic buffer. Only cells able to activate the ATPase maintain a… CONTINUE READING