Activation of transcription factors in a mouse lung following exposure to environmental chemical and biological agents.

Abstract

Environmental biological and chemical agents can modulate innate and acquired immunity in the lung via the stimulation of Toll-like receptors (TLRs). To investigate the effect of environmental chemical agents on the activation of NF-κB and activator protein (AP)-1 subunits and the role of TLR4 signaling in the lung, C3H/HeN and C3H/HeJ (TLR4-defective) mice… (More)
DOI: 10.2131/jts.40.559

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