[Activation of the spinal extracellular signal-regulated kinase is involved in morphine dependence and naloxone-precipitated withdrawal response].

Abstract

Extracellular signal-regulated kinase (ERK), a mitogen-activated protein kinase (MAPK), transduces a broad range of extracellular stimuli into diverse intracellular responses. It has been reported that ERK is involved in the modulation of nociceptive information and central sensitization produced by intense noxious stimuli or peripheral tissue inflammation… (More)

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@article{He2005ActivationOT, title={[Activation of the spinal extracellular signal-regulated kinase is involved in morphine dependence and naloxone-precipitated withdrawal response].}, author={Jian-hua He and Jun-li Cao and Yan-bing Xu and Xue-song Song and Hai-lei Ding and Yin-ming Zeng}, journal={Sheng li xue bao : [Acta physiologica Sinica]}, year={2005}, volume={57 5}, pages={557-65} }