Activation of the phosphatidylinositol metabolic pathway by low molecular weight B cell growth factor.

Abstract

The possible role of phosphatidylinositol breakdown in the induction of proliferation of human activated B cells by low molecular weight B cell growth factor (LMW-BCGF) was examined. LMW-BCGF was found to induce a rapid rise in the concentration of inositol trisphosphate (InsP3) in [3H]inositol-loaded B cell blasts, obtained by prior anti-mu antibody… (More)

Topics

  • Presentations referencing similar topics