Activation of the p21 pathway of growth arrest and apoptosis by the beta 4 integrin cytoplasmic domain.

@article{Clarke1995ActivationOT,
  title={Activation of the p21 pathway of growth arrest and apoptosis by the beta 4 integrin cytoplasmic domain.},
  author={A S Clarke and Margaret M. Lotz and Connie Chao and Arthur M Mercurio},
  journal={The Journal of biological chemistry},
  year={1995},
  volume={270 39},
  pages={22673-6}
}
The integrin alpha 6 beta 4, a receptor for members of the laminin family of basement membrane components, contributes to the function of epithelial cells and their oncogenically transformed derivatives. In our efforts to study alpha 6 beta 4-mediated functions in more detail and to assess the contribution of the beta 4 cytoplasmic domain in such functions… CONTINUE READING