Activation of the inflammatory response system: A new look at the etiopathogenesis of major depression.

@article{West1999ActivationOT,
  title={Activation of the inflammatory response system: A new look at the etiopathogenesis of major depression.},
  author={Dirk van West and Michael Maes},
  journal={Neuro endocrinology letters},
  year={1999},
  volume={20 1-2},
  pages={11-17}
}
Major depression is accompanied by various direct and indirect indicators of a moderate activation of the inflammatory response system (IRS). Increased production of proinflammatory cytokines, such as interleukin-1 (IL-1), IL-6 and interferon (IFNgamma), may play a crucial role in the immune and acute phase response in depression. Lower serum zinc and… CONTINUE READING