Activation of the epidermal growth factor receptor by respiratory syncytial virus results in increased inflammation and delayed apoptosis.

@article{Monick2005ActivationOT,
  title={Activation of the epidermal growth factor receptor by respiratory syncytial virus results in increased inflammation and delayed apoptosis.},
  author={Martha M. Monick and Kelli Cameron and Janice M Staber and Linda S. Powers and Timur O. Yarovinsky and John G. Koland and Gary W. Hunninghake},
  journal={The Journal of biological chemistry},
  year={2005},
  volume={280 3},
  pages={2147-58}
}
Respiratory syncytial virus (RSV) preferentially infects lung epithelial cells. Infection by RSV leads to an extended inflammatory response, characterized by the release of interleukin-8 (IL-8). Activation of ERK MAP kinase is required for both RSV-induced inflammation and the extended survival of infected cells. In this study, we analyzed the role of the… CONTINUE READING