Activation of the coagulation cascade in patients with leptospirosis.

  title={Activation of the coagulation cascade in patients with leptospirosis.},
  author={Wirongrong Chierakul and Panatsaya Tientadakul and Yupin Suputtamongkol and Vanaporn Wuthiekanun and Kriangsak Phimda and Roongrueng Limpaiboon and Nisarat Opartkiattikul and Nicholas J White and Sharon J Peacock and Nicholas P J Day},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  volume={46 2},
BACKGROUND Disseminated intravascular coagulation (DIC) is common among patients with sepsis. Leptospirosis is an important cause of sepsis in tropical areas, and pulmonary hemorrhage associated with thrombocytopenia is the major cause of death, but the coagulopathy in severe leptospirosis has not been further characterized. The aim of this study was to evaluate coagulation factors and the presence of DIC in patients with leptospirosis in northeast Thailand. METHODS We measured plasma… CONTINUE READING


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Disease notification report, Ministry of Public Health, Thailand

  • Chierakul
  • Available at:…
  • 2006
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