Activation of the chicken type I interferon response by infectious bronchitis coronavirus.

@article{Kint2015ActivationOT,
  title={Activation of the chicken type I interferon response by infectious bronchitis coronavirus.},
  author={Joeri Kint and Marcela M Fernandez-Gutierrez and Helena J Maier and Paul Britton and Martijn A. Langereis and Joseph T. M. Koumans and Geert Frits Wiegertjes and Maria Forlenza},
  journal={Journal of virology},
  year={2015},
  volume={89 2},
  pages={1156-67}
}
UNLABELLED Coronaviruses from both the Alphacoronavirus and Betacoronavirus genera interfere with the type I interferon (IFN) response in various ways, ensuring the limited activation of the IFN response in most cell types. Of the gammacoronaviruses that mainly infect birds, little is known about the activation of the host immune response. We show that the prototypical Gammacoronavirus, infectious bronchitis virus (IBV), induces a delayed activation of the IFN response in primary renal cells… CONTINUE READING
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