Activation of the Stress Axis and Neurochemical Alterations in Specific Brain Areas by Concentrated Ambient Particle Exposure with Concomitant Allergic Airway Disease

@inproceedings{Sirivelu2006ActivationOT,
  title={Activation of the Stress Axis and Neurochemical Alterations in Specific Brain Areas by Concentrated Ambient Particle Exposure with Concomitant Allergic Airway Disease},
  author={Madhu P. Sirivelu and Sheba M J Mohankumar and James G. Wagner and Jack R. Harkema and Puliyur S. Mohankumar},
  booktitle={Environmental health perspectives},
  year={2006}
}
OBJECTIVE Exposure to ambient particulate matter (PM) has been linked to respiratory diseases in people living in urban communities. The mechanism by which PM produces these diseases is not clear. We hypothesized that PM could act on the brain directly to stimulate the stress axis and predispose individuals to these diseases. The purpose of this study was to test if exposure to PM can affect brain areas involved in the regulation of neuroendocrine functions, especially the stress axis, and to… CONTINUE READING

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