Activation of the Pseudomonas aeruginosa AlgU regulon through mucA mutation inhibits cyclic AMP/Vfr signaling.

@article{Jones2010ActivationOT,
  title={Activation of the Pseudomonas aeruginosa AlgU regulon through mucA mutation inhibits cyclic AMP/Vfr signaling.},
  author={Adriana K. Jones and Nanette B Fulcher and Grant J Balzer and Mark L Urbanowski and Christopher L Pritchett and Michael J. Schurr and Timothy L. Yahr and Matthew C Wolfgang},
  journal={Journal of bacteriology},
  year={2010},
  volume={192 21},
  pages={5709-17}
}
Pseudomonas aeruginosa is an opportunistic pathogen that causes acute, invasive infections in immunocompromised individuals and chronic, persistent respiratory infections in individuals with cystic fibrosis (CF). The differential progression of acute or chronic infections involves the production of distinct sets of virulence factors. P. aeruginosa strains isolated from patients with acute respiratory infection are generally nonencapsulated and express a variety of invasive virulence factors… CONTINUE READING
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