Activation of spinal GABAB receptors normalizes N-methyl-D-aspartate receptor in diabetic neuropathy.


N-methyl-D-aspartate receptor (NMDAR) activity is increased, while GABAB receptor is downregulated in the spinal cord dorsal horn in diabetic neuropathy. In this study, we determined the interaction of NMDARs and GABAB receptors in streptozotocin (STZ)-induced diabetic neuropathy. The paw withdrawal threshold (PWT) was significantly lower in STZ-treated… (More)
DOI: 10.1016/j.jns.2014.04.002



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