Activation of protein kinase C isoforms and its impact on diabetic complications.

@article{Geraldes2010ActivationOP,
  title={Activation of protein kinase C isoforms and its impact on diabetic complications.},
  author={Pedro Geraldes and George L King},
  journal={Circulation research},
  year={2010},
  volume={106 8},
  pages={1319-31}
}
Both cardio- and microvascular complications adversely affect the life quality of patients with diabetes and have been the leading cause of mortality and morbidity in this population. Cardiovascular pathologies of diabetes have an effect on microvenules, arteries, and myocardium. It is believed that hyperglycemia is one of the most important metabolic… CONTINUE READING