Activation of protein kinase C augments evoked transmitter release

@article{Shapira1987ActivationOP,
  title={Activation of protein kinase C augments evoked transmitter release},
  author={Roy Shapira and Shai D. Silberberg and Simona Ginsburg and Rami Rahamimoff},
  journal={Nature},
  year={1987},
  volume={325},
  pages={58-60}
}
In view of the emerging role of the phosphoinositide system in cellular communication1,2 we examined its involvement in quantal transmitter release, which is a key element in synaptic transmission3. Transmitter release is normally activated by an increase in intracellular calcium, achieved either by entry of calcium ions through the presynaptic membrane4,5 or by intracellular calcium liberation6. One of the targets of the phosphoinositide signalling system is the enzyme protein kinase C (PKC… CONTINUE READING

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