Activation of porcine factor VIII:C by thrombin and factor Xa.

@article{Lollar1985ActivationOP,
  title={Activation of porcine factor VIII:C by thrombin and factor Xa.},
  author={P Lollar and Gaylord J. Knutson and David Fass},
  journal={Biochemistry},
  year={1985},
  volume={24 27},
  pages={8056-64}
}
The activation of porcine factor VIII:C by thrombin and by factor Xa was studied by a chromogenic substrate assay and by sodium dodecyl sulfate-polyacrylamide gel radioelectrophoresis of 125I-labeled factor VIII:C activation products. In the chromogenic assay, the kinetics of factor VIII:C dependent activation of factor X by factor IXa in the presence of calcium and phosphatidylserine/phosphatidylcholine vesicles were measured with N-benzoyl-L-isoleucyl-L-glutamylglycyl-L-arginine p… CONTINUE READING

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