Activation of peroxisome proliferator-activated receptor gamma inhibits the growth of human pancreatic cancer.

@article{Sasaki2001ActivationOP,
  title={Activation of peroxisome proliferator-activated receptor gamma inhibits the growth of human pancreatic cancer.},
  author={Takanori Sasaki and Yuka Fujimoto and Akihiko Tsuchida and Yasushi Kawasaki and Yukio Kuwada and Kazuaki Chayama},
  journal={Pathobiology : journal of immunopathology, molecular and cellular biology},
  year={2001},
  volume={69 5},
  pages={258-65}
}
OBJECTIVE In the present study, we examined the expression of peroxisome proliferator-activated receptor gamma (PPARgamma) in human pancreatic cancer and the possible effects of its ligand engagement on cell growth. METHODS Seven human pancreatic cancer cell lines and 7 surgically resected human pancreatic cancer tissues were used as samples. The expression of PPARgamma was analyzed with reverse transcription-polymerase chain reaction and immunoblotting. The interaction between PPARgamma and… CONTINUE READING