Activation of p53 signaling initiates apoptotic death in a cellular model of Parkinson’s disease


Mitochondrial dysfunction caused by oxidative stress and genetic defects have been implicated in the loss of dopaminergic neurons in Parkinson’s disease. However, the key molecular events that provoke neurodegeneration still remain poorly understood. We recently showed that shortly after exposure to oxidative stress, only those cells showing phosphorylation… (More)
DOI: 10.1007/s10495-006-6316-3


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