Activation of p38 MAPK by oxidative stress underlying epirubicin-induced vascular endothelial cell injury.

Abstract

Epirubicin, an anthracycline antitumor drug, often causes vascular injury such as vascular pain, phlebitis, and necrotizing vasculitis. However, an effective prevention for the epirubicin-induced vascular injury has not been established. The purpose of this study is to identify the mechanisms of cell injury induced by epirubicin in porcine aorta endothelial… (More)
DOI: 10.1016/j.freeradbiomed.2012.02.003

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