Activation of p38 MAPK and expression of TGF-β1 in rat colon enterocytes after whole body γ-irradiation.

Abstract

PURPOSE To examine the p38 mitogen-activated protein kinase (p38) phosphorylation and transforming growth factor beta 1 (TGF-β1) expression in rat colon enterocytes after irradiation and their contribution to pathology of intestinal radiation disease. MATERIALS AND METHODS Male Wistar rats were irradiated with whole body γ-radiation of 0.5, 1, 2, 3, 4, 5… (More)
DOI: 10.3109/09553002.2012.654044

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