Activation of p 34 cdc 2 protein kinase activity in meiotic and mitotic cell cycles in mouse oocytes and embryos

@inproceedings{Choi2005ActivationOP,
  title={Activation of p 34 cdc 2 protein kinase activity in meiotic and mitotic cell cycles in mouse oocytes and embryos},
  author={Taesaeng Choi and Fugaku Aoki and Makoto Mori and Masakane Yamashita and Yoshitaka Nagahama and Kaoru Kohmoto},
  year={2005}
}
p34 protein kinase is a universal regulator of M-phase in eukaryotic cell cycle. To investigate the regulation of meiotic and mitotic cell cycle in mammals, we examined the changes in phosphorylation states of p34 and its histone HI kinase activity in mouse oocytes and embryos. We showed that p34 has three different migrating bands (referred to as upper, middle and lower bands) on SDS-PAGE followed by immunoblotting with antiPSTAIR antibody, and that the upper and middle bands are… CONTINUE READING
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