Activation of nucleotide oligomerization domain containing protein 1 induces lipolysis through NF-κB and the lipolytic PKA activation in 3T3-L1 adipocytes.

@article{Purohit2013ActivationON,
  title={Activation of nucleotide oligomerization domain containing protein 1 induces lipolysis through NF-κB and the lipolytic PKA activation in 3T3-L1 adipocytes.},
  author={Jaanki Shamb Purohit and Pan Hu and Guoxun Chen and Jay Whelan and Naima Moustaid-Moussa and Ling Zhao},
  journal={Biochemistry and cell biology = Biochimie et biologie cellulaire},
  year={2013},
  volume={91 6},
  pages={428-34}
}
Obesity is associated with chronic inflammation. Toll-like receptors (TLR) and NOD-like receptors (NLR) are two families of pattern recognition receptors that play important roles in the immune response and inflammation in adipocytes. Activation of TLR4 has been shown to stimulate lipolysis from adipose tissue or adipocytes. However, effects of activation… CONTINUE READING