Activation of nucleolar and extranucleolar RNA synthesis and changes in the ribosomal content of human embryos developing in vitro.

@article{Tesaik1986ActivationON,
  title={Activation of nucleolar and extranucleolar RNA synthesis and changes in the ribosomal content of human embryos developing in vitro.},
  author={Jan Tesařik and V{\'a}clay Kope{\vc}ny and Michelle Plachot and Jacqueline Mandelbaum},
  journal={Journal of reproduction and fertility},
  year={1986},
  volume={78 2},
  pages={463-70}
}
RNA synthetic activity of human 2-16-cell embryos developing in vitro was studied by [3H]uridine light-microscope autoradiography. Parallelly cut thin sections were examined in the electron microscope. The first extranucleolar RNA synthesis was detected in 4-cell embryos, but nucleoli were never labelled until the 3rd cleavage (6-8-cell embryos). In 6-cell embryos the nucleolar labelling was mostly confined to a narrow peripheral zone. In later cleavage stages most of the blastomeres showed… CONTINUE READING

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