Activation of natural killer cells by heat shock protein 70.

@article{Multhoff2002ActivationON,
  title={Activation of natural killer cells by heat shock protein 70.},
  author={Gabriele Multhoff},
  journal={International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group},
  year={2002},
  volume={18 6},
  pages={
          576-85
        }
}
Intracellular heat shock proteins (HSP) function as molecular chaperones, they support folding and transport mechanisms of other proteins under physiological conditions and following physical or chemical stress. More recently, extracellular localized HSP have been found to play key roles in the induction of a cellular immune response. Either they act as carrier molecules for immunogenic peptides that are presented on Antigen Presenting Cells (APC) to cytotoxic T-cells or they themselves act as… CONTINUE READING

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