Activation of muscle fibers in individual motor units revealed by 2-deoxyglucose-6-phosphate.

@article{Nemeth1988ActivationOM,
  title={Activation of muscle fibers in individual motor units revealed by 2-deoxyglucose-6-phosphate.},
  author={Patti M. Nemeth and Barbara J. Norris and Oliver H. Lowry and Debra A. Gordon and Roger M. Enoka and Douglas Stuart},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1988},
  volume={8 11},
  pages={3959-66}
}
Motor units of the cat tibialis posterior muscle were selectively activated by prolonged electrical stimulation of functionally isolated motor axons in situ. During the activation, the glucose analog 2-deoxyglucose (DG) was administered systemically. Single muscle fibers were subsequently examined for accumulation of the metabolite 2-deoxyglucose-6-phosphate (DG6P) by an analytical assay and for depletion of glycogen by a PAS glycogen-specific staining reaction (periodic acid Schiff; PAS). In… CONTINUE READING