Activation of mitochondrial fusion provides a new treatment for mitochondria-related diseases.

Abstract

Mitochondria fragmentation destabilizes mitochondrial membranes, promotes oxidative stress and facilitates cell death, thereby contributing to the development and the progression of several mitochondria-related diseases. Accordingly, compounds that reverse mitochondrial fragmentation could have therapeutic potential in treating such diseases. BGP-15, a… (More)
DOI: 10.1016/j.bcp.2018.01.038

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