Activation of mitochondrial function and Hb expression in non‐haematopoietic cells by an EPO inducer ameliorates ischaemic diseases in mice

@article{Hsu2013ActivationOM,
  title={Activation of mitochondrial function and Hb expression in non‐haematopoietic cells by an EPO inducer ameliorates ischaemic diseases in mice},
  author={Pei-Lun Hsu and L. Horng and Kang-Yung Peng and Chia-ling Wu and Hui-Ching Sung and Rong-Tsun Wu},
  journal={British Journal of Pharmacology},
  year={2013},
  volume={169}
}
Many organs suffer from ischaemic injuries that reduce their ability to generate sufficient energy, which is required for functional maintenance and repair. Erythropoietin (EPO) ameliorates ischaemic injuries by pleiotropic effects. The aim of this study was to investigate the effect and mechanism of a small molecule EH‐201, and found it as a potent EPO inducer and its effect in non‐haematopoietic cells for therapeutic potential in ischemic disorders. 
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