Activation of microglial cells and complement following traumatic injury in rat entorhinal-hippocampal slice cultures.

@article{Bellander2004ActivationOM,
  title={Activation of microglial cells and complement following traumatic injury in rat entorhinal-hippocampal slice cultures.},
  author={Bo-Michael Bellander and Olof Bendel and Gabriel von Euler and Marcus Ohlsson and Mikael Svensson},
  journal={Journal of neurotrauma},
  year={2004},
  volume={21 5},
  pages={
          605-15
        }
}
The complement cascade has been suggested to be involved in development of secondary brain damage following traumatic brain injury (TBI). Previous studies have shown that reactive microglia are involved in activation of the complement cascade following various injuries to the nervous system. Macrophages seem to have a significant role in this process, but it is still unclear whether these cells, as well as the complement components, are derived from reactive microglia or if these biological… CONTINUE READING
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