Activation of metabotropic glutamate receptors by repetitive stimulation in auditory cortex.

@article{Bandrowski2002ActivationOM,
  title={Activation of metabotropic glutamate receptors by repetitive stimulation in auditory cortex.},
  author={Anita E. Bandrowski and Stephen L Moore and John H. Ashe},
  journal={Synapse},
  year={2002},
  volume={44 3},
  pages={146-57}
}
To determine whether metabotropic glutamate receptors (mGluRs) contribute to the responses of neurons to repetitive stimulation in the rat auditory cortex in vitro, five stimulus pulses were delivered at 2-100 Hz which elicited five depolarizing synaptic responses, f-EPSPs: f-EPSPs(1-5). Stimulus pulses 2-5 delivered at low frequencies (2-10 Hz) elicited f-EPSPs(2-5) that were about 15% smaller than the response elicited by the first pulse (f-EPSP(1)). In the presence of the nonspecific mGluR… CONTINUE READING
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