Activation of latent Ca2+ channels in renal epithelial cells by parathyroid hormone

@article{Bacskai1990ActivationOL,
  title={Activation of latent Ca2+ channels in renal epithelial cells by parathyroid hormone},
  author={Brian J. Bacskai and P. A. Friedman},
  journal={Nature},
  year={1990},
  volume={347},
  pages={388-391}
}
CALCIUM has an important role in regulating epithelial cell ion transport1,2 and is itself transported by tissues involved in the maintenance of extracellular Ca2+ homeostasis3–6. Although the mechanism of Ca2+ entry in electrically excitable cells is well-documented7,8 little is known about it in epithelial cells. Calcium absorption in polarized epithelial cells is a two-step process in which Ca2+ enters cells across apical plasma membranes and is extruded across basolateral membranes9. Efflux… CONTINUE READING

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