Activation of kinin B1 receptor evokes hyperthermia through a vagal sensory mechanism in the rat


Kinins are mediators of pain and inflammation. Their role in thermoregulation is, however, unknown despite the fact the B1 receptor (B1R) was found implicated in lipopolysaccharide (LPS)-induced fever. The aim of this study was to investigate the mechanism by which peripheral B1R affects body core temperature in a rat model known to show up-regulated levels… (More)
DOI: 10.1186/1742-2094-9-214


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