Activation of intracellular pathways with forskolin and phorbol ester increases LHRH mRNA level in the rat hypothalamus superfused in vitro.

@article{Lee1990ActivationOI,
  title={Activation of intracellular pathways with forskolin and phorbol ester increases LHRH mRNA level in the rat hypothalamus superfused in vitro.},
  author={Byung Ju Lee and Ki Hean Kim and Won Kyoo Cho},
  journal={Brain research. Molecular brain research},
  year={1990},
  volume={8 3},
  pages={185-91}
}
Two intracellular signal transduction mechanisms such as cAMP-protein kinase a and phosphatidylinositol (PI) turnover-protein kinase c are known to be dually involved in the regulation of luteinizing hormone-releasing hormone (LHRH) release. However, it is not yet evident that the activation of two intracellular pathways affects the LHRH gene expression… CONTINUE READING