Activation of in vitro matured mouse oocytes arrested at first or second meiotic metaphase.

@article{Polaski1995ActivationOI,
  title={Activation of in vitro matured mouse oocytes arrested at first or second meiotic metaphase.},
  author={Zbigniew Polański},
  journal={The International journal of developmental biology},
  year={1995},
  volume={39 6},
  pages={1015-20}
}
Some mammalian oocytes fail to complete maturation in vitro and arrest development at the first metaphase stage. The response of such blocked oocytes to sperm penetration was investigated. Ovarian mouse oocytes from two inbred strains, CBA/Kw and KE, were cultured in vitro for 20 h. Both oocytes arrested at the first metaphase (MI oocytes) and second metaphase (MII oocytes) were then inseminated. The majority of MII and MI oocytes reinitiated meiosis in response to sperm penetration, although… CONTINUE READING

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