Activation of human neutrophils by a synthetic anti-microbial peptide, KLKLLLLLKLK-NH2, via cell surface calreticulin.

Abstract

We previously reported that a synthetic anti-bacterial peptide, KLKLLLLLKLK-NH2 (L5), showed significant chemotherapeutic activity in methicillin-resistant Staphylococcus aureus-infected mice, and its ability to activate human neutrophils was related to its chemotherapeutic activity. In this study, we found that activation of neutrophils by L5 was inhibited… (More)

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Cite this paper

@article{Cho1999ActivationOH, title={Activation of human neutrophils by a synthetic anti-microbial peptide, KLKLLLLLKLK-NH2, via cell surface calreticulin.}, author={Ja Hyun Cho and Kazuaki Homma and Shiro Kanegasaki and Shunji Natori}, journal={European journal of biochemistry}, year={1999}, volume={266 3}, pages={878-85} }