Activation of human T cells by the superantigen Staphylococcus enterotoxin B: analysis on a cellular level.

Abstract

Superantigens interact with and activate a sizeable fraction of T cells characterized by expression of specific V beta gene segments of their antigen receptor. The massive activation of T cells in an organism is considered responsible for clinical symptoms associated with superantigen-producing bacteria. Here we studied the in vitro activation of human T… (More)

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