Activation of human AML14.3D10 eosinophils by nanoparticles: Modulatory activity on apoptosis and cytokine production.

@article{Vallires2016ActivationOH,
  title={Activation of human AML14.3D10 eosinophils by nanoparticles: Modulatory activity on apoptosis and cytokine production.},
  author={Francis Valli{\`e}res and Jean-Christophe Simard and Claudie No{\"e}l and Maxime Murphy-Marion and Val{\'e}rie Lavastre and Denis Girard},
  journal={Journal of immunotoxicology},
  year={2016},
  volume={13 6},
  pages={
          817-826
        }
}
Eosinophilic inflammation is frequently observed in response to nanoparticle (NP) exposure in airway rodent models of allergies where the number of eosinophils is increased in lungs. Despite this, it is surprising that the potential cytotoxic effect of NP, as well as their direct role on eosinophils is poorly documented. The present study investigated how different NP can alter the biology of the human eosinophilic cell line AML14.3D10. It was found that among NP forms of CeO2, ZnO, TiO2, and… CONTINUE READING
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