Activation of follicle development: the primordial follicle.

  title={Activation of follicle development: the primordial follicle.},
  author={Helen M. Picton},
  volume={55 6},
Investigations of primordial follicle formation and growth are fundamental to our understanding of female gamete production. In all mammalian females the full complement of oocytes is established during fetal development. This store of primordial follicles is not renewable and serves the entire reproductive life span of the adult. The correct programming of fetal ovarian development and the number of primordial follicles formed will therefore limit the fecundity of the ovary. Primordial… CONTINUE READING