Activation of focal adhesion kinase by hepatitis B virus HBx protein: multiple functions in viral replication.

@article{Bouchard2006ActivationOF,
  title={Activation of focal adhesion kinase by hepatitis B virus HBx protein: multiple functions in viral replication.},
  author={Michael J. Bouchard and Lihua Wang and Robert J Schneider},
  journal={Journal of virology},
  year={2006},
  volume={80 9},
  pages={4406-14}
}
The hepatitis B virus (HBV) X protein (HBx) is a multifunctional regulator of cellular signal transduction and transcription pathways and has a critical role in HBV replication. Much of the cytoplasmic signal transduction activity associated with HBx expression and its stimulation of viral replication is attributable to HBx-induced activation of calcium signaling pathways involving Pyk2 and Src tyrosine kinases. To further characterize upstream signal transduction pathways that are required for… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 34 extracted citations

Similar Papers

Loading similar papers…