Activation of extracellular signal-regulated kinases during dehydration in the African clawed frog, Xenopus laevis.

@article{Malik2009ActivationOE,
  title={Activation of extracellular signal-regulated kinases during dehydration in the African clawed frog, Xenopus laevis.},
  author={Amal Malik and Kenneth B. Storey},
  journal={The Journal of experimental biology},
  year={2009},
  volume={212 Pt 16},
  pages={2595-603}
}
In its native environment the African clawed frog, Xenopus laevis, can experience seasonally arid conditions that impose dehydration stress. Activation of intracellular signal transduction cascades can mediate and coordinate biochemical responses to ameliorate dehydration stress. This study examines the extracellular signal-regulated kinase (ERK) signaling cascade, analyzing responses of both upstream and downstream components in six tissues of X. laevis experiencing medium and high levels of… CONTINUE READING