Activation of epithelial Na channels by hormonal and autoregulatory mechanisms of action

@article{Els1991ActivationOE,
  title={Activation of epithelial Na channels by hormonal and autoregulatory mechanisms of action},
  author={Willem J. Els and Sandy I. Helman and T Mencio},
  journal={The Journal of General Physiology},
  year={1991},
  volume={98},
  pages={1197 - 1220}
}
Methods of blocker-induced noise analysis were used to investigate the way in which forskolin and vasopressin stimulate Na transport at apical membranes of short-circuited frog skin transporting Na at spontaneous rates of transport. Experiments were done under conditions where the apical Ringer solution contained either 100 mM Na or a reduced Na concentration of 5 or 10 mM Na and buffered with either HCO3 or HEPES. Reduction of apical solution Na concentration caused a large autoregulatory… CONTINUE READING
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