Activation of ephrin A proteins influences hematopoietic stem cell adhesion and trafficking patterns.

@article{Ting2010ActivationOE,
  title={Activation of ephrin A proteins influences hematopoietic stem cell adhesion and trafficking patterns.},
  author={Michael Y. J. Ting and Bryan William Day and Mark Damien Spanevello and Andrew W. Boyd},
  journal={Experimental hematology},
  year={2010},
  volume={38 11},
  pages={1087-98}
}
OBJECTIVE To determine if Eph receptors and ephrins can modulate the homing of hematopoietic cells in a murine bone marrow transplantation model. MATERIALS AND METHODS EphA and ephrin A gene expression by mouse hematopoietic stem cells and the progenitor cell line FDCP-1 was determined by real-time reverse transcription polymerase chain reaction and flow cytometry. The effect of ephrin A activation on adhesion of hematopoietic progenitors was determined by in vitro adhesion assays in which… CONTINUE READING
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