Activation of dimeric ABA receptors elicits guard cell closure, ABA-regulated gene expression, and drought tolerance

@article{Okamoto2013ActivationOD,
  title={Activation of dimeric ABA receptors elicits guard cell closure, ABA-regulated gene expression, and drought tolerance},
  author={Masanori Okamoto and Francis C. Peterson and Andrew Defries and Sang-Youl Park and Akira Endo and Eiji Nambara and Brian F. Volkman and Sean R. Cutler},
  journal={Proceedings of the National Academy of Sciences},
  year={2013},
  volume={110},
  pages={12132 - 12137}
}
Abscisic acid (ABA) is an essential molecule in plant abiotic stress responses. It binds to soluble pyrabactin resistance1/PYR1-like/regulatory component of ABA receptor receptors and stabilizes them in a conformation that inhibits clade A type II C protein phosphatases; this leads to downstream SnRK2 kinase activation and numerous cellular outputs. We previously described the synthetic naphthalene sulfonamide ABA agonist pyrabactin, which activates seed ABA responses but fails to trigger… 

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