Activation of developmental nuclear fibroblast growth factor receptor 1 signaling and neurogenesis in adult brain by α7 nicotinic receptor agonist.

@article{Narla2013ActivationOD,
  title={Activation of developmental nuclear fibroblast growth factor receptor 1 signaling and neurogenesis in adult brain by α7 nicotinic receptor agonist.},
  author={Sridhar T. Narla and Ilona Klejbor and Barbara G Birkaya and Yu-Wei Lee and Joanna M. Moryś and Ewa K. Stachowiak and Dorota Prokop and Merouane Bencherif and Michal K. Stachowiak},
  journal={Stem cells translational medicine},
  year={2013},
  volume={2 10},
  pages={776-88}
}
Reactivation of endogenous neurogenesis in the adult brain or spinal cord holds the key for treatment of central nervous system injuries and neurodegenerative disorders, which are major health care issues for the world's aging population. We have previously shown that activation of developmental integrative nuclear fibroblast growth factor receptor 1 (FGFR1) signaling (INFS), via gene transfection, reactivates neurogenesis in the adult brain by promoting neuronal differentiation of brain neural… CONTINUE READING

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