Activation of cardiac chloride conductance by the tyrosine kinase inhibitor, genistein

@article{Shuba1996ActivationOC,
  title={Activation of cardiac chloride conductance by the tyrosine kinase inhibitor, genistein},
  author={L. Shuba and T. Asai and S. Pelzer and T. Mcdonald},
  journal={British Journal of Pharmacology},
  year={1996},
  volume={119}
}
1 Genistein (GST), an inhibitor of protein tyrosine kinase (PTK), Na3VO4 (VO4), an inhibitor of phosphotyrosine phosphatase (PTPase), and forskolin (FSK), an activator of the cyclic AMP‐dependent, cystic fibrosis transmembrane conductance regulator (CFTR) Cl− channel, were applied to guinea‐pig ventricular myocytes to probe for a possible role of tyrosine phosphorylation in the regulation of cardiac Cl− channels. 2 Myocytes in the standard whole‐cell configuration were pulsed to various… Expand
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