Activation of c-fos expression in hypothalamic nuclei by mu- and kappa-receptor agonists: correlation with catecholaminergic activity in the hypothalamic paraventricular nucleus.

@article{Laorden2000ActivationOC,
  title={Activation of c-fos expression in hypothalamic nuclei by mu- and kappa-receptor agonists: correlation with catecholaminergic activity in the hypothalamic paraventricular nucleus.},
  author={Mar{\'i}a Luisa Alem{\'a}n Laorden and Mar{\'i}a Teresa Castells and M. D. Rivero Mart{\'i}nez and Paco Jim{\'e}nez Mart{\'i}nez and Mar{\'i}a Victoria Milan{\'e}s},
  journal={Endocrinology},
  year={2000},
  volume={141 4},
  pages={
          1366-76
        }
}
Administration of the preferential mu-opioid receptor agonist, morphine, and selective K-opioid receptor agonists elicits activation of the hypothalamus-pituitary-adrenocortical axis, although the site or the molecular mechanisms for these effects have not been determined. The expression ofFos, the protein product of the c-fos protooncogene, has been widely used as an anatomical marker of monitoring neuronal activity. In the present study we evaluated 1) the effects of the mu-opioid receptor… CONTINUE READING

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