Activation of apoptosis signalling pathways by reactive oxygen species.

  title={Activation of apoptosis signalling pathways by reactive oxygen species.},
  author={Maureen Redza-Dutordoir and Diana A. Averill-Bates},
  journal={Biochimica et biophysica acta},
  volume={1863 12},
Reactive oxygen species (ROS) are short-lived and highly reactive molecules. The generation of ROS in cells exists in equilibrium with a variety of antioxidant defences. At low to modest doses, ROS are considered to be essential for regulation of normal physiological functions involved in development such as cell cycle progression and proliferation, differentiation, migration and cell death. ROS also play an important role in the immune system, maintenance of the redox balance and have been… CONTINUE READING
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