Activation of apoptosis and its inhibition.

@article{Miller1999ActivationOA,
  title={Activation of apoptosis and its inhibition.},
  author={Douglas K. Miller},
  journal={Annals of the New York Academy of Sciences},
  year={1999},
  volume={886},
  pages={
          132-57
        }
}
The induction of apoptosis, or controlled cell death, by various stimuli has been shown to activate a cascade of endoproteases, called caspases, that cleave numerous cellular proteins necessary for cellular homeostasis. This review discusses this family of proteases together with a variety of mammalian and viral regulatory proteins that act to control this activation. 
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